Supplier & Manufacturer of Minoxidil in India

Minoxidil

Minoxidil is a vasodilator that relaxes (widens) blood vessels and improves blood flow

Minoxidil is used to treat severely high blood pressure (hypertension) that is causing symptoms or damaging your vital organs. Minoxidil is usually given together with two other medicines to help prevent serious side effects.

Minoxidil tablets should not be used to promote scalp hair growth. Only the topical form of minoxidil (Rogaine) is recommended for that use.

Minoxidil may also be used for purposes not listed in this medication guide.

Certificate of Analysis

Description
White or Off-white crystalline powder.
Result
White crystalline powder.
Identification (by IR)
Should match with Standard.
Result
Complies.
pH (in a mixture with water (1.5: 100)
3.0 – 4.0
Result
3.5
Moisture content
NMT 2.0 %
Result
0.5 %
Residue on Ignition
NMT 0.5 %
Result
0.2 %
Minoxidil content (by HPLC)
50.0 – 60.0 % w/w.
Result
54.1 % w/w.
Oxothiazolidine Carboxylic AcidContent (By titration)
40.0 % – 50.0 % w/w.
Result
40.9 % w/w.

Note: Note: – We are leading channel partner of much API manufacturer, supplier & exporters and Pharmaceutical raw material in Colombo, Chili, Ecuador and Globally.

Material Safety Data Sheet

Section 1 – Chemical Product
Product Identifier
Minoxidil
MSDS Prepared By
R&D Department
Section 2 – Composition / Information Of Ingredients
Product Name
Minoxidil
Synonym
6-(Piperidin-1-yl)pyrimidine-2,4-diamine 3-oxide
CAS Number
38304-91-5
Section 3 – HAZARDOUS IDENTIFICATION
Hazard Class and Category Code(s)
Acute Toxic Oral
4
Skin Irritant
2
Eye Irritant
2
Stot Se
3
Hazard Statement Code(s)
H302
Harmful if swallowed.
H315
Causes skin irritation.
H319
Causes serious eye irritation.
H335
May cause respiratory irritation.
Precautionary Statement
P261
Avoid breathing dust / fume / gas / mist / vapours / spray.
P264
Wash hands & other exposed areas thoroughly after handling.
P301+P312
IF SWALLOWED: Call a POSION CENTER or doctor / physician if you feel unwell.
P330
Rinse mouth.
P280
Wear protective gloves / protective clothing / eye protection / face protection.
P305+P351+P338
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present & easy to do. Continue rising.
P501
Dispose of contents / containers in accordance with local regulation.
Single Word
Warning
Section 4 – FIRST AID
General Information
If exposed or concerned. Get medical advice / attention.
Eye Contact
Remove contact lenses, if work & rinse open eye with at least 15 minutes under running water & apply sterile protective bandage. Obtain medical attention immediately.
Skin Contact
Remove contaminated clothing & wash affected area with soap & water immediately. If irritation or redness occurs obtain immediate medical attention.
Inhalation
Move to fresh air. Assure fresh air breathing. If breathing has ceased give artificial respiration. Obtain immediate medical attention.
Ingestion
Never give anything by mouth if patient is unconscious. Do not induce vomiting. Rinse mouth with water & obtain immediate medical attention.
Other Information
Treat symptomatically.
Section 5 – FIRE FIGHTING MEASURES
Suitable Extinguishing Media
Use extinguishing media appropriate for surrounding fire. Water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Exposure Hazards
Carbon oxides, nitrogen oxides.
Fire Fighting Procedures
A self-contained breathing apparatus & suitable protective clothing should be worn by fire fighters.
Section 6 – ACCIDENT RELEASE MEASURES
Personal Precautions
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas, avoid breathing dust.
Environmental Precautions
Do not let enter drains.
Disposal
Disposal of waste in accordance with all applicable federal, state and local laws.
Methods for Cleaning-up
Take up mechanically or sweep up carefully & transfer to a suitable container for recovery or waste disposal. Avoid generation of dust. Ventilate the area & wash spill site after material pick-up is complete.
Section 7 – HANDLING AND STORAGE
Handling
Avoid contact with skin & eyes. Avoid formation of dust & aerosols. Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection.
Storage
Store in cool place. Keep container tightly closed in a dry & well-ventilated place.
Section 8 – EXPOSURE CONTROLS / PERSONAL PROTECTION
Exposure Controls
Handle in accordance with good industrial hygiene & safety practice. Wash hands before breaks & at the end of workday.
Occupational Exposure Controls
Wear recommended personal protective equipment as details below.
Personal Protection
Chemical resistant gloves & safety glasses is must.
Respiratory Protection
Seek professional advice prior to respirator selection. Atmospheric level should be maintained below exposure limit. If airborne concentrations is high use mask or respirator.
Hand Protection
Wear chemical protective gloves.
Eye Protection
Wear Safety glasses.
Skin Protection
Wear chemical protective clothing.
Work Practices
Eye wash facilities & a safety shower should be easily accessible. Before breaks & at the end of work thoroughly wash hands with soap & water. Wash contaminated clothing before use. Clean footwear before use.
Environmental exposure Controls
All necessary precautions must be taken to avoid release into the environment. Refer to Local, State or Nationals Legislations for environment & pollution control.
Section 9 – PHYSICAL AND CHEMICAL PROPERITIES
Appearance
Crystalline, White powder
Odour
N/A
Odour Threshold
N/A
pH
N/A
Melting Point / Freezing Point
Melts with approx. 248° – 268° C with decomposition
Initial Boiling Point
N/A
Flash Point
N/A
Evaporation Rate
N/A
Flammability
N/A
Upper Explosive Limit
N/A
Lower Explosive Limit
N/A
Vapor Pressure
N/A
Vapor Density
N/A
Relative Density
N/A
Solubility(ies)
Soluble in alcohol & in propylene glycol, sparingly soluble in methanol, slightly soluble in water, practically insoluble in chloroform, in acetone, in ethyl acetate & in hexane.
Partition Coefficient
N/A
Auto-Ignition Temperature
N/A
Decomposition Temperature
N/A
Viscosity
N/A
Explosive Properties
N/A
Oxidising Properties
N/A
Section 10 – STABILITY AND REACTIVITY
Stable
Stable & no hazardous polymerization.
Condition to avoid
Usual precautions for handling of chemicals should be observed.
Material to Avoid
Avoid contact with oxidizing substances.
Reactivity
N/A
Section 11 – TOXICOLOGICAL INFORMATION
Acute Toxicity
LD50 Oral (Rat) 1321 mg/kg
Ingestion
Harmful if swallowed.
Inhalation
May cause respiratory irritation.
Skin Contact
May be harmful if absorbed through skin. Causes skin irritation.
Eye Contact
Causes serious eye irritation.
Section 12 – ECOLOGICAL INFORMATION
Aquatic Toxicity
N/A
Persistence & Degradability
N/A
Bioaccumulate Potential
N/A
Mobility in Soil
N/A
Other adverse Effects
N/A
Section 13 – DISPOSAL CONSIDERATION
Waste Treatment
Contact a licensed professional waste disposal service to dispose of this material. Dispose in a safe manner in accordance with local / national regulations.
Section 14 – TRANSPORT INFORMATION
D.O.T. Label
None
Land Transport
ADR / RID / GGVS / GGVE UN NO
None / Not Regulated
Sea Transport
IMDG
None / Not Regulated
Air Transport
IATA
None / Not Regulated
Section 15 – REGULATORY INFORMATION
Hazard Class and Category Code(s)
Acute Toxic Oral
4
Skin Irritant
2
Eye Irritant
2
Stot Se
3
Hazard Statement Code(s)
H302
Harmful if swallowed.
H315
Causes skin irritation.
H319
Causes serious eye irritation.
H335
May cause respiratory irritation.
Single Word
Warning
Section 16 – OTHER INFORMATION
Atilus Pharma provides information contained herein in good faith but makes no representation as to its comprehensives or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product.
Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.
ATILUS PHARMA MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESSED OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OR MERCHANTABILITY, FITNESS FOR A PARTICULER PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT WHICH THE INFORMATION REEFERS. GLOBAL PHARMA WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF RELIANCE UPON THIS INFORMATION.